|
KMID : 1156220190450030258
|
|
Journal of Environmental Health Sciences
2019 Volume.45 No. 3 p.258 ~ p.266
|
|
|
Comparison of Blood Lead Concentration Using Graphite Furnace Atomic Absorption Spectrometry (GF-AAs) and Inductively Coupled Plasma-mass Spectrometry (ICP-MS)
|
|
Kang Min-Kyung
Kwon Jung-Yeon
Kim Byoung-Gwon
Lim Hyoun-Ju
Seo Jeong-Wook
Kim Yu-Mi
Hong Young-Seoub
|
|
|
Abstract
|
|
|
Objectives: In this study, blood lead was analyzed using graphite furnace atomic absorption spectrometry (GFAAs) and inductively coupled plasma mass spectrometry (ICP-MS). We tried to examine the difference and consistency of the analytical values and the applicability of the analytical method.
Methods: We selected 57 people who agreed to participate in this study. After confirming the linearity of the calibration standard curves in GF-AAs and ICP-MS, the concentrations of lead in quality control material and samples were measured, and the degree of agreement was compared.
Results: The detection limit of the ICP-MS was lower than that of GF-AAs. The coefficient of variation of reference materials was shown to be stable in the ICP-MS and GF-AAs. When the correspondence between the two equipments was verified by bias of the analysis values, a concordance was shown, and approximately 98% of the ideal reference lines were present within ±40% of the deflection.
Conclusion: GF-AAs showed high sensitivity to single heavy metal analysis, but it took much time and showed higher detection limit than ICP-MS. Therefore, it would be considered necessary to switch to ICP-MS analysis method, considering that the level of lead exposure is gradually decreasing.
|
|
|
KEYWORD
|
|
|
Lead, ICP-MS, GF-AAs, degree of agreement
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|